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Popular and/or Featured Works
Muhammad Asad   
truly it is they, they who in the life to come shall be the losers
The Clear Quran, Dr. Mustafa Khattab   
Without a doubt, they will be the worst losers in the Hereafter.
Safi Kaskas   
Assuredly, in the life to come, they will lose the most.

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Source Arabic and Literal tools
Arabic   
‏لَا جَرَمَ أَنَّهُمْ فِى ٱلْءَاخِرَةِ هُمُ ٱلْأَخْسَرُونَ ‎
Transliteration (2021)   
lā jarama annahum fī l-ākhirati humu l-akhsarūn
Word for Word
Dr. Shehnaz Shaikh, Ms. Kauser Katri, and more
  
No doubt that they in the Hereafter [they] (will be) the greatest losers.

Generally Accepted Translations of the Meaning
Muhammad Asad   
truly it is they, they who in the life to come shall be the losers
M. M. Pickthall   
Assuredly in the Hereafter they will be the greatest losers
Yusuf Ali (Saudi Rev. 1985)   
Without a doubt, these are the very ones who will lose most in the Hereafter
The Clear Quran, Dr. Mustafa Khattab   
Without a doubt, they will be the worst losers in the Hereafter.
Safi Kaskas   
Assuredly, in the life to come, they will lose the most.
Wahiduddin Khan   
In the Hereafter, it is they who shall be the greatest losers
Shakir   
Truly in the hereafter they are the greatest losers
Dr. Laleh Bakhtiar   
Without a doubt they in the world to come, they are the ones who are losers.
T.B.Irving   
It is positive they will lose most in the Hereafter!
Abdul Hye   
Certainly, they are those who will be the greatest losers in the Hereafter.
The Study Quran   
There is no doubt that in the Hereafter they shall be the greatest losers
Dr. Kamal Omar   
No doubt! That they, in the Hereafter: they are the greatest losers
M. Farook Malik   
No doubt they will be the greatest losers in the Hereafter
Talal A. Itani (new translation)   
Without a doubt, in the Hereafter, they will be the biggest losers
Muhammad Mahmoud Ghali   
No question that they are the ones (who are) the greatest losers in the Hereafter
Muhammad Sarwar   
In the life to come they will certainly lose a great deal
Muhammad Taqi Usmani   
Essentially, they are the worst losers in the Hereafter
Shabbir Ahmed   
These fabricators will be the worst losers in the Hereafter
Dr. Munir Munshey   
No doubt at all! They will be the real losers in the life-to-come
Syed Vickar Ahamed   
No doubt, they are the greatest losers in the Hereafter
Umm Muhammad (Sahih International)   
Assuredly, it is they in the Hereafter who will be the greatest losers
[The Monotheist Group] (2011 Edition)   
There is no doubt, that in the Hereafter they are the greatest losers
Abdel Haleem   
There is no doubt they will be the ones to lose most in the life to come
Abdul Majid Daryabadi   
Undoubtedly they! in the Hereafter they shall be the greatest losers
Ahmed Ali   
Undoubtedly they will be losers in the life to come
Aisha Bewley   
Without question they will be the greatest losers in the Next World.
Ali Ünal   
Without doubt, in the Hereafter they will be the greatest losers
Ali Quli Qara'i   
Undoubtedly, they are the ones who will be the biggest losers in the Hereafter
Hamid S. Aziz   
No doubt in the Hereafter these are the greatest losers
Ali Bakhtiari Nejad   
Without a doubt, they are the worst losers in the hereafter
A.L. Bilal Muhammad et al (2018)   
Without a doubt, these are the very ones who will lose most in the hereafter
Musharraf Hussain   
Without doubt, they will be the biggest losers in the Hereafter.
Maududi   
Doubtlessly, they shall be the greatest losers in the Hereafter.
[The Monotheist Group] (2013 Edition)   
There is no doubt, that in the Hereafter they are the greatest losers.
Mohammad Shafi   
No doubt, they are the ones that shall in the Hereafter be doomed

Controversial or status undetermined works
Ahmed Raza Khan (Barelvi)   
Willing or not willing, it is they who are the greatest losers in the Hereafter.
Rashad Khalifa   
There is no doubt that, in the Hereafter, they will be the worst losers.
Hasan Al-Fatih Qaribullah   
without doubt they will be the greatest losers in the Everlasting Life
Maulana Muhammad Ali   
Truly in the Hereafter they are the greatest losers
Muhammad Ahmed & Samira   
Undoutably/certainly that they (are) in the end (other life), they are the most losers
Bijan Moeinian   
Beyond any shadow of the doubt they will be the worse losers in the Hereafter
Faridul Haque   
They will be, unnecessarily, the greatest losers in the Hereafter
Sher Ali   
Undoubtedly, it is they who shall be the greatest losers in the Hereafter
Dr. Mohammad Tahir-ul-Qadri   
This is absolutely true that it is certainly they who will be the greatest losers in the Hereafter
Amatul Rahman Omar   
No doubt, it is these who shall be the worst losers in the Hereafter
Muhsin Khan & Muhammad al-Hilali   
Certainly, they are those who will be the greatest losers in the Hereafter

Non-Muslim and/or Orientalist works
Arthur John Arberry   
they without doubt will be the greatest losers in the world to come
George Sale   
There is no doubt but they shall be most miserable in the world to come
Edward Henry Palmer   
No doubt but that in the hereafter these are those who lose
John Medows Rodwell   
There is no doubt but that in the next world they shall be the lost ones
N J Dawood (2014)   
and in the life to come they will assuredly lose most

New, Partial, or In Progress Translations
Linda “iLHam” Barto   
Without a doubt, they will lose the most in the afterlife.
Irving & Mohamed Hegab   
Certainly, they will lose the most in the Hereafter!
Sayyid Qutb   
Most certainly, it is they who in the life to come shall be the greatest losers.
Ahmed Hulusi   
The truth is they will be the ones in the greatest loss in the eternal life to come.
Sayyed Abbas Sadr-Ameli   
Assuredly, they will be the greatest losers in the Hereafter.
Al-muntakhab fi tafsir al-Qur‘an al-Karim   
It is no wonder shall they be great losers Hereafter
Mir Aneesuddin   
Assuredly, they will be the losers in the hereafter.

Obsolete and/or older editions
Yusuf Ali (Orig. 1938)   
Without a doubt, these are the very ones who will lose most in the Hereafter
OLD Literal Word for Word   
No doubt that they in the Hereafter [they] (will be) the greatest losers
OLD Transliteration   
La jarama annahum fee al-akhirati humu al-akhsaroona