Until We open upon them a gate of intense suffering, suddenly they will be left hopeless in that suffering.
Sayyed Abbas Sadr-Ameli
Until, when We open against them a gate of severe chastisement, behold! They will get into despair at it
Al-muntakhab fi tafsir al-Qur'an al-Karim
They persisted in wrong -doing until We closed the gate of mercy in their faces and opened the gate of torture and put them to torment (that they may be brought back to their senses) But to the contrary. they only nursed despair which led to recklessness and to heedlessness arising from despair