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Popular and/or Featured Works
Muhammad Asad
He creates man out of a [mere] drop of sperm: and lo! this same being shows himself endowed with the power to think and to argue
The Clear Quran, Dr. Mustafa Khattab
He created humans from a sperm-drop, then—behold!—they openly challenge ˹Him˺.
Safi Kaskas
He created the human being out of a fertilized ovum, and suddenly he is an open adversary.

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Source Arabic and Literal tools
Arabic
خَلَقَ الْإِنسَانَ مِن نُّطْفَةٍ فَإِذَا هُوَ خَصِيمٌ مُّبِين
Transliteration
Khalaqa al-insana min nutfatin fa-itha huwa khaseemun mubeenun
Transliteration-2
khalaqa l-insāna min nuṭ'fatin fa-idhā huwa khaṣīmun mubīnu
Word for Word
Dr. Shehnaz Shaikh, Ms. Kauser Katri, and more
He created the human kind from a minute quantity of semen then behold, he (is) an opponent clear.

Generally Accepted Translations of the Meaning
Muhammad Asad
He creates man out of a [mere] drop of sperm: and lo! this same being shows himself endowed with the power to think and to argue
M. M. Pickthall
He hath created man from a drop of fluid, yet behold! he is an open opponent
Yusuf Ali (Saudi Rev. 1985)
He has created man from a sperm-drop; and behold this same (man) becomes an open disputer
The Clear Quran, Dr. Mustafa Khattab
He created humans from a sperm-drop, then—behold!—they openly challenge ˹Him˺.
Safi Kaskas
He created the human being out of a fertilized ovum, and suddenly he is an open adversary.
Wahiduddin Khan
He created man out of a [mere] drop of sperm: yet he shows himself to be openly contentious
Shakir
He created man from a small seed and lo! he is an open contender
Dr. Laleh Bakhtiar
He created the human being from seminal fluid. That is when he is a clear adversary.
T.B.Irving
He creates man from a drop of semen, yet he is an open opponent;
Abdul Hye
He has created human from semen, yet the he becomes an open opponent.
The Study Quran
He created man from a drop, and behold, he is a manifest adversary
Dr. Kamal Omar
He created the human being from Nutfah, and afterwards he (behaves as) one who indulges in all sorts of arguments and disputes
Farook Malik
He created man from a drop of semen, yet he is an open contender
Talal A. Itani (new translation)
He created the human being from a drop of fluid, yet he becomes an open adversary
Muhammad Mahmoud Ghali
He created man of a sperm-drop; yet, (behold) how he is an evident adversary
Muhammad Sarwar
He created the human being from a drop of fluid but the human being openly disputes His Word
Muhammad Taqi Usmani
He created man from a drop, and soon he turned into a debating person, expressing himself openly
Shabbir Ahmed
He created the human being out of male and female gametes. They should be humble before their Creator's Messages instead of being contentious
Dr. Munir Munshey
He created man from a drop of fluid. Yet, man is now hostile and argumentative
Syed Vickar Ahamed
He has created man from a drop of semen (sperm); And look this same (man) becomes an open challenger (about the creation)
Umm Muhammad (Sahih International)
He created man from a sperm-drop; then at once, he is a clear adversary
[The Monotheist Group] (2011 Edition)
He created man from a seed, but then he becomes clearly in opposition
Abdel Haleem
He created man from a drop of fluid, and yet man openly challenges Him
Abdul Majid Daryabadi
He hath created man from a drop, and Lo! he is a disputer open
Ahmed Ali
Man He created from a drop of semen; and still he becomes an open contender
Aisha Bewley
He created man from a drop of sperm and yet he is an open challenger!
Ali Ünal
He has created human from (so slight a beginning as) a mere drop of seminal fluid; and yet, he turns into an open, fierce adversary (selfishly disputing against the truth)
Ali Quli Qara'i
He created man from a drop of [seminal] fluid, and, behold, he is an open contender
Hamid S. Aziz
He created man from a drop (of sperm); and yet, behold, he is an open opponent
Ali Bakhtiari Nejad
God created the human being from fertilized egg (zygote), then he is an overt challenger now
A.L. Bilal Muhammad et al (2018)
He has created the human being from a zygote, and behold, he becomes an open disputer
Musharraf Hussain
He created Humans from a drop of semen, so is that why humans are quarrelsome
Maududi
He created man out of a mere drop of fluid, and lo! he turned into an open wrangler
[The Monotheist Group] (2013 Edition)
He has created man from a seed, but then he becomes clearly in opposition.
Mohammad Shafi
He (Allah) created man from tiny fertilized ovum. And, lo, he has become an open adversary

Controversial or status undetermined works
Ahmed Raza Khan (Barelvi)
He created man from a purified drop; therefore, he is an open disputer.
Rashad Khalifa
He created the human from a tiny drop, then he turns into an ardent opponent.
Hasan Al-Fatih Qaribullah
He created mankind from a sperm drop, yet he is a clear adversary
Maulana Muhammad Ali
He created man from a small life-germ, and lo! he is an open contender
Muhammad Ahmed - Samira
He created the human/mankind from a drop/male's or female's secretion/little water, so then he (the human/mankind) is (a) clear/evident disputer/adversary
Bijan Moeinian
He has created mankind from a tiny embryo; how funny of this insignificant creature to turn against his own soul and challenge his Creator
Faridul Haque
He created man from a drop of fluid, yet he is an open quarreller
Sher Ali
HE has created man from a mere drop of fluid, but lo ! he is an open disputer
Dr. Mohammad Tahir-ul-Qadri
He alone has created man from a drop of vital fluid, yet he has become openly contentious (instead of becoming totally submissive to Allah)
Amatul Rahman Omar
He has created human being from a mere drop of fluid, (a small life germ) then look! what a perspicuous and sound debater he has turned out to be
Muhsin Khan & Muhammad al-Hilali
He has created man from Nutfah (mixed drops of male and female sexual discharge), then behold, this same (man) becomes an open opponent

Non-Muslim and/or Orientalist works
Arthur John Arberry
He created man of a sperm-drop; and, behold, he is a manifest adversary
George Sale
He hath created man of seed; and yet behold, he is a professed disputer against the resurrection
Edward Henry Palmer
He created man from a clot; and yet, behold, he is an open opponent
John Medows Rodwell
Man hath He created from a moist germ; yet lo! man is an open caviller
N J Dawood (2014)
He created man from a little germ: yet is he openly contentious

New, Partial, or In Progress Translations
Linda “iLHam” Barto
He has created humanity from a single cell; look how the same becomes a public disputant.
Sayyid Qutb
He creates man out of a drop of sperm; yet this same man is openly contentious.
Ahmed Hulusi
He created man from a single sperm... And behold, he has become defiant!
Sayyed Abbas Sadr-Ameli
He created man out of semen, yet behold! He is an open adversary.
Al-muntakhab fi tafsir al-Qur'an al-Karim
He created the Adamite from a constituent part of fluid that is emitted*, yet he -the Adamite- is more ready to argue than to obey. He brings forward reasons against Allah with a strong, capacious and argumentative mind
Mir Aneesuddin
He created man from a sperm, even then he is an open disputant .

Obsolete and/or older editions
Yusuf Ali (Orig. 1938)
He has created man from a sperm-drop; and behold this same (man) becomes an open disputer
OLD Literal Word for Word
He created the human kind from a minute quantity of then behold, he (is) an opponent clear